Southern Squash Casserole

Total Time: 55 mins Difficulty: Beginner
Savor the comfort of Southern traditions with this creamy and cheesy Squash Casserole!
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There’s something deeply satisfying about a dish that feels like a warm hug on the plate, and this Southern Squash Casserole does just that. Rich and creamy, it features tender yellow squash nestled in a cheesy blend of sour cream and mayonnaise, all crowned with a buttery, crunchy cracker topping. Whether you’re new to Southern recipes or a seasoned home cook, this beginner-friendly casserole (with just 20 minutes of prep time and 30 minutes of baking) is about to become a weeknight staple. With only a handful of simple ingredients and easy techniques, you’ll be dishing out a comforting side that pairs perfectly with grilled chicken, roast pork, or a casual potluck spread. Plus, at around 300 calories per serving, you can savor the flavor without overdoing it.

As each forkful delivers a warm, velvety bite of squash and cheddar, you can almost taste the history of comfort food winding through every mouthful. This isn’t just any vegetable dish—it’s a celebration of Southern traditions, where the crackle of crushed butter crackers on top gives way to a melty, dreamy interior. From the very first scoop, you’ll notice how effortlessly the flavors of yellow squash and sharp cheddar meld with the tang of sour cream, bringing out the best of a cheesy casserole without overwhelming the palate. Get ready to enjoy a culinary hug in every slice and share stories of family gatherings, backyard barbecues, and cozy dinners—because this is more than just a recipe, it’s a memory-maker.

KEY INGREDIENTS IN SOUTHERN SQUASH CASSEROLE

Before diving into the kitchen, it helps to know what makes this casserole truly special. Each ingredient contributes a unique layer of taste, texture, and Southern charm. From crisp squash to that irresistible cracker topping, here’s what you’ll need to craft this comforting dish.

  • Yellow squash

Provides a tender, slightly sweet base that soaks up the creamy sauce. Its mild flavor lets the cheese and seasonings shine while adding a vibrant golden hue.

  • Onion

Offers a savory depth, balancing the sweetness of the squash. When softened, it brings a gentle bite and helps meld the other flavors together.

  • Cheddar cheese

Imparts a sharp, tangy richness that turns the casserole indulgent. As it melts, it weaves throughout the squash mixture for gooey pockets of deliciousness.

  • Mayonnaise

Creates a smooth, velvety texture and binds the ingredients. It also adds a hint of tanginess that complements the cheese.

  • Sour cream

Adds creamy body and a subtle tang that brightens every bite. It keeps the casserole moist and balanced.

  • Salt

Enhances all the natural flavors, from squash to cheese. A well-seasoned dish brings out the best in each ingredient.

  • Black pepper

Adds a gentle heat and aromatic depth. Freshly ground pepper provides little bursts of spice in each forkful.

  • Eggs

Act as a natural binder, holding the casserole together as it bakes. They also lend a light, custard-like richness.

  • Butter crackers

Create a golden, crunchy topping that contrasts beautifully with the creamy interior. Crushing them releases that buttery flavor all over the surface.

  • Butter

Melts into the cracker crumbs, promoting browning and adding a luscious, toasty taste to the topping.

HOW TO MAKE SOUTHERN SQUASH CASSEROLE

Now that you’ve gathered your ingredients, let’s walk through how to transform them into a bubbling, golden casserole. This process is straightforward, making it perfect for home cooks of any skill level. Follow each step carefully and watch as simple components come together in harmony.

1. Preheat your oven to 350°F (175°C). Ensuring the oven is fully heated before baking helps the casserole cook evenly from the moment it goes in.

2. In a large pot, bring water to a rolling boil. Add the sliced squash and chopped onion, then cook until the squash is just tender, about 5 minutes. Drain thoroughly in a colander and set aside so excess moisture doesn’t make the casserole soggy.

3. In a spacious bowl, combine the drained squash and onion with shredded cheddar cheese, mayonnaise, sour cream, salt, pepper, and the beaten eggs. Use a sturdy spoon or spatula to stir everything until the mixture is smooth, creamy, and uniformly blended.

4. Lightly grease a 9×13-inch baking dish with butter or nonstick spray. Pour the squash mixture into the dish and spread it out evenly, ensuring a flat top for an even cracker crust.

5. In another bowl, mix the crushed butter crackers with the melted butter. Toss gently until every crumb is coated. Then sprinkle this buttery crumb mixture over the top of your squash filling, covering it in a golden layer.

6. Place the baking dish on the center rack and bake for 25–30 minutes. Watch for a golden-brown topping and a bubbly surface indicating that the interior is heated through and set.

7. Remove the casserole from the oven and let it cool for a few minutes. This rest time helps the dish set, making it easier to serve neat slices without losing any of that creamy goodness.

SERVING SUGGESTIONS FOR SOUTHERN SQUASH CASSEROLE

When it comes to enjoying this comforting squash casserole, the real magic happens in how you present and pair it. Whether you’re serving a cozy family dinner or hosting a casual cookout, these ideas will elevate your dish and make every bite memorable.

  • Pair with grilled meats

Serve alongside juicy grilled chicken, pork chops, or steak to balance the creamy texture with smoky, savory flavors. The contrast enhances both dishes and creates a complete Southern-style plate.

  • Garnish with fresh herbs

Sprinkle chopped parsley, chives, or thyme on top just before serving. The fresh green notes add a pop of color and a hint of brightness that cuts through the richness.

  • Add a crisp salad

Present a simple green salad dressed with a tangy vinaigrette for a refreshing side that offsets the casserole’s creaminess. Think mixed lettuce, cherry tomatoes, and cucumber slices for a light crunch.

  • Serve in individual ramekins

Portion the mixture into small, oven-safe ramekins before baking to create personalized servings. Guests will love their own quaint casserole, and it makes for charming presentation at holiday dinners or potlucks.

HOW TO STORE SOUTHERN SQUASH CASSEROLE

Whether you’re meal-prepping for the week or saving leftovers for another day, proper storage keeps this squash casserole tasting fresh and delicious. A little planning goes a long way in preserving the creamy interior and crunchy topping without sacrificing texture or flavor.

Storing in the refrigerator ensures the casserole stays moist and prevents the dairy ingredients from spoiling. If you know you won’t eat it within a few days, freezing is an excellent way to extend its shelf life while maintaining quality. When reheating, using the oven or toaster oven helps re-crisp the topping, so each bite retains that signature crunch. For ultimate convenience, consider assembling the casserole in its baking dish, then covering and refrigerating before baking — that way, it’s ready to slide straight into the oven when hunger strikes.

  • Refrigerator storage

Allow the casserole to cool completely, then cover tightly with plastic wrap or aluminum foil. Store in the refrigerator for up to 4 days. When ready to serve, reheat in a 350°F oven until warmed through.

  • Freezer method

Cool the casserole, then wrap the baking dish with two layers of foil or place portions in airtight freezer containers. Freeze for up to 3 months. Thaw overnight in the fridge before reheating.

  • Reheating tips

Preheat your oven to 325°F and bake the refrigerated or thawed casserole (uncovered) for 15–20 minutes. For an extra-crispy topping, switch to broil for the last 2–3 minutes, watching closely to avoid burning.

  • Make-ahead assembly

Prepare the filling and topping separately, then cover and refrigerate both components in their bowls. When you’re ready to bake, assemble in a greased dish and follow the baking instructions. This method saves time on busy days.

CONCLUSION

This creamy, cheesy Southern Squash Casserole is a true testament to the comforts of Southern cooking, combining tender yellow squash with a luscious blend of cheddar, sour cream, and mayonnaise, all crowned by a golden cracker crust. We’ve walked through every step—from boiling and mixing to baking and resting—so you can confidently recreate this homestyle favorite in your own kitchen. With just 20 minutes of prep and 30 minutes in the oven, you’ll have a soul-satisfying side dish that’s perfect for beginner cooks and seasoned foodies alike. Be sure to print this article and save it for future dinners or special gatherings; you’ll find a FAQ section below to help answer any lingering questions.

If you give this casserole a try, please leave a comment or question—your feedback helps other cooks feel at home here. Let me know how the flavors turned out, whether you experimented with a cheese blend or added a pinch of cayenne for heat. I love hearing about your personal twists and serving ideas. Feel free to share any hurdles you faced or tips you discovered along the way. Whether it’s pairing suggestions or storage hacks, your insights make this community kitchen feel even warmer and more inviting. Happy cooking!

Southern Squash Casserole

Difficulty: Beginner Prep Time 20 mins Cook Time 30 mins Rest Time 5 mins Total Time 55 mins
Calories: 300

Description

Rich and creamy, this Southern Squash Casserole bursts with the classic flavors of yellow squash, cheddar, and crunchy cracker topping, making it the perfect side dish for any meal.

Ingredients

Instructions

  1. Preheat your oven to 350°F (175°C).
  2. In a large pot, bring water to a boil. Add sliced squash and chopped onion. Cook until tender, about 5 minutes. Drain well and set aside.
  3. In a large bowl, mix the drained squash and onion with cheddar cheese, mayonnaise, sour cream, salt, pepper, and beaten eggs. Stir until well combined.
  4. Pour the mixture into a lightly greased 9x13-inch baking dish, spreading it out evenly.
  5. In another bowl, combine the crushed butter crackers and melted butter. Sprinkle this over the top of the squash mixture in the baking dish.
  6. Bake in the preheated oven for 25-30 minutes, or until the top is golden brown and the casserole is bubbly.
  7. Remove from oven and let cool for a few minutes before serving.

Note

  • Yellow squash is typically used, but you can substitute with zucchini if desired.
  • For a bit of spice, add a pinch of cayenne pepper to the mixture.
  • This casserole pairs well with grilled meats for a Southern-style meal.
  • Consider using a blend of cheeses for a more complex flavor.
  • The dish can be prepared ahead of time and baked just before serving.
Keywords: squash casserole, Southern recipes, comfort food, cheesy casserole, vegetable dishes, easy dinner

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Frequently Asked Questions

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Can I use zucchini instead of yellow squash for this casserole?

Yes, you can substitute zucchini for yellow squash in this recipe. Zucchini will provide a similar texture and flavor, while still allowing you to enjoy the delicious casserole.

Can I make this casserole ahead of time?

Absolutely! You can prepare the casserole up to the point of baking, cover it with plastic wrap or aluminum foil, and refrigerate it for up to 24 hours. When you're ready to bake, remove it from the fridge and let it sit at room temperature for about 30 minutes before placing it in the preheated oven.

What can I serve with Southern Squash Casserole?

This casserole pairs wonderfully with grilled meats such as chicken, pork, or steak. It also goes well with cornbread and a simple green salad for a complete Southern-style meal.

How do I store leftovers, and how long will they last?

Store any leftover casserole in an airtight container in the refrigerator for up to 3-5 days. You can reheat it in the oven at 350°F (175°C) until warmed through, or use a microwave for quicker reheating.

Can I add additional ingredients to customize the casserole?

Definitely! You can add ingredients like cooked crumbled bacon, diced bell peppers, or herbs such as thyme or basil for extra flavor. If you enjoy a bit of spice, consider adding a pinch of cayenne pepper to the mixture as well.

Anna Dubois

Food and Lifestyle Blogger

Hello and welcome to my kitchen! I’m Anna Dubois a passionate home cook, recipe developer, and lover of rustic, wholesome meals made with heart. I grew up in the French countryside, where food was more than nourishment, it was a way to connect, to celebrate, and to create memories.

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